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Anti-CD3 Antibody
品牌：Antibodies
貨號(hào)：
規(guī)格：100μg
貨期：
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Anti-CD3 Antibody
商品詳情 參考文獻(xiàn) 相關(guān)資料
Name: Anti-CD3 Antibody
See all CD3 primary antibodies
Description: Mouse monoclonal (OKT3) antibody to CD3.
Specificity: The mouse monoclonal antibody OKT3 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.
Applications: FC, IHC-Fr, FUNC
Reactivity: Human
Immunogen: Human PBMCs.
Host: Mouse
Clonality: Monoclonal
Clone: OKT3
Isotype: IgG2a
Conjugate: Unconjugated
Purification: Protein A chromatography.
Concentration: 1 mg/ml
Purity: > 95% (by SDS-PAGE)
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.4, without Azide (0.2 μm filter sterilised). Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.
Storage: Store at 2-8°C.
Function: Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
Involvement in Disease: Immunodeficiency 25: An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens.
Sequence Similarities: Belongs to the CD3Z/FCER1G family.
Post-Translational Modification: Phosphorylated on Tyr residues after T-cell receptor triggering.
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 915?Human
  • Entrez Gene: 916?Human
  • Entrez Gene: 917?Human
  • Entrez Gene: 919?Human
  • Omim: 186740?Human
  • Omim: 186780?Human
  • Omim: 186790?Human
  • Omim: 186830?Human
  • SwissProt: P04234?Human
  • SwissProt: P07766?Human
  • SwissProt: P09693?Human
  • SwissProt: P20963?Human
  • Unigene: 156445?Human
  • Unigene: 2259?Human
  • Unigene: 3003?Human
  • Unigene: 504048?Human
    		•
    Synonyms:
  • 4930549J05Rik Antibody
  • A430104F18Rik Antibody
  • AW552088 Antibody
  • Cd247 Antibody
  • CD247 antigen Antibody
  • CD247 antigen, zeta subunit Antibody
  • CD247 molecule Antibody
  • CD3 Antibody
  • CD3 antigen, delta subunit Antibody
  • CD3 delta Antibody
  • CD3 epsilon Antibody
  • CD3 eta Antibody
  • CD3 gamma Antibody
  • CD3 molecule delta polypeptide Antibody
  • CD3 molecule, epsilon polypeptide Antibody
  • CD3 molecule, gamma polypeptide Antibody
  • CD3 zeta Antibody
  • CD3-DELTA Antibody
  • CD3d Antibody
  • CD3D antigen delta polypeptide Antibody
  • CD3d antigen, delta polypeptide (TiT3 complex) Antibody
  • CD3d molecule delta Antibody
  • CD3d molecule delta CD3 TCR complex Antibody
  • CD3d molecule, delta (CD3-TCR complex) Antibody
  • CD3D_HUMAN Antibody
  • CD3E Antibody
  • CD3e antigen Antibody
  • CD3E antigen epsilon polypeptide Antibody
  • CD3e antigen, epsilon polypeptide (TiT3 complex) Antibody
  • CD3e molecule epsilon Antibody
  • CD3e molecule epsilon CD3 TCR complex Antibody
  • CD3e molecule, epsilon (CD3-TCR complex) Antibody
  • CD3epsilon Antibody
  • CD3G Antibody
  • CD3g antigen Antibody
  • CD3G antigen gamma polypeptide Antibody
  • CD3g antigen, gamma polypeptide (TiT3 complex) Antibody
  • CD3g molecule gamma Antibody
  • CD3g molecule gamma CD3 TCR complex Antibody
  • CD3g molecule, gamma (CD3-TCR complex) Antibody
  • CD3H Antibody
  • CD3Q Antibody
  • CD3Z Antibody
  • CD3zeta Antibody
  • Ctg3 Antibody
  • FLJ17620 Antibody
  • FLJ17664 Antibody
  • FLJ18683 Antibody
  • FLJ79544 Antibody
  • FLJ94613 Antibody
  • IMD19 Antibody
  • Leu-4 Antibody
  • MGC138597 Antibody
  • OKT3, delta chain Antibody
  • OTTHUMP00000032544 Antibody
  • T cell receptor Antibody
  • T cell receptor T3 delta chain Antibody
  • T cell receptor T3 gamma chain Antibody
  • T cell receptor T3 zeta chain Antibody
  • T cell receptor zeta chain Antibody
  • T cell surface glycoprotein CD3 Antibody
  • T cell surface glycoprotein CD3 delta chain Antibody
  • T cell surface glycoprotein CD3 epsilon chain Antibody
  • T cell surface glycoprotein CD3 gamma chain Antibody
  • T cell surface glycoprotein CD3 zeta chain Antibody
  • T-cell antigen receptor complex, delta subunit of T3 Antibody
  • T-cell antigen receptor complex, epsilon subunit of T3 Antibody
  • T-cell antigen receptor complex, gamma subunit of T3 Antibody
  • T-cell antigen receptor complex, zeta subunit of CD3 Antibody
  • T-cell receptor T3 delta chain Antibody
  • T-cell receptor T3 gamma chain Antibody
  • T-cell surface antigen T3/Leu-4 epsilon chain Antibody
  • T-cell surface glycoprotein CD3 delta chain Antibody
  • T-cell surface glycoprotein CD3 gamma chain Antibody
  • T3 Antibody
  • T3d Antibody
  • T3e Antibody
  • T3g Antibody
  • T3z Antibody
  • TCRE Antibody
  • TCRk Antibody
  • Tcrz Antibody
  • TCRzeta Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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