亚洲欧美日韩中文在线制服,中文在线最新版天堂,制服 丝袜 国产,亚洲伊人久久大香线蕉,亚洲精品乱码久久久久久蜜桃

訂購信息
上海拜力生物科技公司
Tel:400-968-7988    021-33779008
Anti-ETHE1 Antibody
品牌：Antibodies
貨號(hào)：
規(guī)格：100μl
貨期：
應(yīng)用： 點(diǎn)擊這里給我發(fā)消息  咨詢客服

Anti-ETHE1 Antibody
商品詳情 參考文獻(xiàn) 相關(guān)資料
Name: Anti-ETHE1 Antibody
See all ETHE1 primary antibodies
Description: Rabbit polyclonal antibody to ETHE1
Specificity: The antibody detects endogenous levels of total ETHE1 protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Fusion protein corresponding to residues near the N terminal of human ethylmalonic encephalopathy 1
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.6mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (PubMed:12398897).
Tissue Specificity: Ubiquitously expressed.
Involvement in Disease: Ethylmalonic encephalopathy: Autosomal recessive disorder characterized by neurodevelopmental delay and regression, recurrent petechiae, acrocyanosis, diarrhea, leading to death in the first decade of life. It is also associated with persistent lactic acidemia and ethylmalonic and methylsuccinic aciduria.
Sequence Similarities: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Cellular Location: Cytoplasm. Nucleus. Mitochondrion matrix.
Database Links:
  • Entrez Gene: 23474?Human
  • Entrez Gene: 66071?Mouse
  • Omim: 608451?Human
  • SwissProt: O95571?Human
  • SwissProt: Q9DCM0?Mouse
  • Unigene: 7486?Human
  • Unigene: 29553?Mouse
    		•
    Synonyms:
  • ETHE1 Antibody
  • ETHE1 protein, mitochondrial precursor Antibody
  • ETHE1_HUMAN Antibody
  • ethylmalonic encephalopathy 1 Antibody
  • Ethylmalonic encephalopathy protein 1 Antibody
  • hepatoma subtracted clone one Antibody
  • Hepatoma subtracted clone one protein Antibody
  • HSCO Antibody
  • mitochondrial Antibody
  • Protein ETHE1 Antibody
  • Protein ETHE1 mitochondrial Antibody
  • YF13H12 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    熱銷產(chǎn)品
    熱銷產(chǎn)品排行榜
    • 關(guān)于我們
    • 購物流程
    • 支付方式
    • 配送方式

    請(qǐng)打開QQ掃碼聯(lián)系
    Copyright@ 2003-2025  進(jìn)口試劑采購網(wǎng)版權(quán)所有     

    BIOLEAF熱搜   BIOLEAF試劑盒   BIOLEAF ELISA   BIOLEAF試劑   BIOLEAF品牌   BIOLEAF抗體   BIOLEAF耗材   BIOLEAF小儀器

    sitemap   細(xì)胞庫查詢   危險(xiǎn)品圖標(biāo)

    本公司網(wǎng)站所展示銷售的產(chǎn)品僅供科研！

             滬ICP備08023583號(hào)-6     
    產(chǎn)品咨詢
    QQ掃碼溝通
    在線客服
    服務(wù)電話
    400-968-7988
    掃碼關(guān)注
    微信公眾號(hào)二維碼

    滬公網(wǎng)安備 31011202007338號(hào)