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A general protein kinase inhibitor. CaM, PKC , PKG , myosin light chain kinase .Attached is a published reference from researchers who have used our K-252a product.A receptor-like cytoplasmic kinase, BIK1, associates with a flagellin receptor complex to initiate plant innate immunity.

Additional Information

Product #	K-1006
CAS #	99533-80-9
Chemical Name	(9S,10R,12R)-2,3,9,10,11,12-HEXAHYDRO-10-HYDROXY-9-METHYL-1-OXO-9,12-EPOXY-1H-DIINDOLO[1,2,3-FG-3',2',1'-KL]PYRROLO[3,4-I][1,6]BENZODIAZOCINE-10-CARBOXYLIC ACID METHYL ESTER
Formula	C27H21N3O5
MW	467.5
Appearance	White powder
Purity	>98%
Solubility	May be dissolved in DMSO (100 mg/ml)
Melting Point	256-258 °C
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptors

Additional Information

MDL Number	MFCD00161522
ChemACX	X1286334-4
InChI	InChI=1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18-,26+,27+/m1/s1
SMILES	C[C@@]12[C@](C[C@@H](O1)n3c4ccccc4c5c3c6n2c7ccccc7c6c8c5C(=O)NC8)(C(=O)OC)O