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*Please inquire the availability for this product. Leptomycin A, a methyl analogue of leptomycin B, is a minor component of the leptomycin complex produced by selected Streptomyces species. Leptomycin B is a potent inhibitor of the nuclear transport receptor CRM1. Leptomycin A is also likely to inhibit nuclear transport and may offer differences in exporter selectivity. Leptomycin A shows antimicroMSTl activity against Schizosaccaromyces pombe and Mucor rouxianus.

Additional Information

Synonyms	ATS 1287A, PD 118607, Jildamycin
Product #	L-2533
CAS #	87081-36-5
Formula	C32H46O6
MW	526.7
Appearance	Colourless Film
Purity	>99% by HPLC
Solubility	Soluble in methanol or 100% ethanol
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	An antifungal antibiotic

Additional Information

MDL Number	MFCD01711669
InChI	InChI=1S/C32H46O6/c1-20(16-22(3)12-14-28-24(5)13-15-30(35)38-28)10-9-11-21(2)17-25(6)31(36)27(8)32(37)26(7)18-23(4)19-29(33)34/h9,11-17,19-20,24-28,32,37H,10,18H2,1-8H3,(H,33,34)/b11-9+,14-12+,21-17+,22-16+,23-19+
SMILES	CC1C=CC(=O)OC1/C=C/C(=C/C(C)C/C=C/C(=C/C(C)C(=O)C(C)C(C(C)C/C(=C/C(=O)O)/C)O)/C)/C