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上海拜力生物科技公司
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Oridonin
品牌：AG Scientific
貨號(hào)：
規(guī)格：5 mg
貨期：
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CAS:28597-04-2Formula:C20H28N5O6MW:364.43Appearance:Off-WhiteSolidPurity:97%byHPLC
商品詳情 參考文獻(xiàn) 相關(guān)資料
Oridonin, a diterpenoid isolated from Rabdosia rubescens displays anti-inflammatory, anti-bacterial, anti-tumor effects and has been used for the treatment of human cancers, especially esophageal carcinoma. Exposure to oridonin induces apoptosis in AE (AML1-ETO)-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation of AE at D188

Additional Information

SynonymsNSC-250682
Product #O-2374
CAS #28597-04-2
Chemical Name(1S,4AR,5S,11AS,11BS,14S)-1,5,6,14-TETRAHYDROXY-4,4-DIMETHYL-8-METHYLENEDECAHYDRO-1H-6,11B-(EPOXYMETHANO)-6A,9-METHANOCYCLOHEPTA[A]NAPHTHALEN-7(8H)-ONE
FormulaC20H28N5O6
MW364.43
AppearanceOff-White Solid
Purity97% by HPLC
SolubilityDMSO
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseOridonin induces apoptosis, inhibits migration and invasion on highly-metastatic human breast cancer

Additional Information

MDL NumberMFCD00221762
ChemACXX1273057-7
InChIInChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3
SMILESCC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C
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