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Paraherquamide A, Penicillium simlicissimum
品牌：AG Scientific
貨號(hào)：
規(guī)格：1 mg
貨期：
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CAS:77392-58-6Formula:C28H35N3O5MW:493.6Appearance:WhitePowderPurity:95%byHPLC
商品詳情 參考文獻(xiàn) 相關(guān)資料

Paraherquamide A was first reported as a mycotoxin related to the indole tremorgenic mycotoxins. Subsequent research identified a potent non-toxic paralysis of nematodes which led to the metabolite's development as a candidate anthelmintic. Paraherquamide A is a selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors.

Additional Information

SynonymsAntibiotic VM 29919
Product #P-1470
CAS #77392-58-6
Chemical Name(1R,3S,5R,7S,12R)-12-HYDROXY-4,4,4',4',12,14-HEXAMETHYL-4'H,13H-SPIRO[9,14-DIAZATETRACYCLO[5.5.2.01,9.03,7]TETRADECANE-5,8'-[1,4]DIOXEPINO[2,3-G]INDOLE]-9',13(10'H)-DIONE
FormulaC28H35N3O5
MW493.6
AppearanceWhite Powder
Purity95% by HPLC
SolubilitySoluble in ethanol, methanol, DMF or DMSO
Melting Point290.08 °C
Storage Temp-20°C
UseParaherquamide A was first reported as a mycotoxin related to the indole tremorgenic mycotoxins

Additional Information

MDL NumberMFCD01709427
ChemACXX3299411-3
InChIInChI=1S/C28H35N3O5/c1-23(2)10-12-35-20-17(36-23)8-7-16-19(20)29-21(32)27(16)14-26-15-31-11-9-25(5,34)28(31,22(33)30(26)6)13-18(26)24(27,3)4/h7-8,10,12,18,34H,9,11,13-15H2,1-6H3,(H,29,32)/t18-,25+,26+,27+,28-/m0/s1
SMILESC[C@]1(CCN2[C@]13C[C@@H]4[C@](C2)(C[C@@]5(C4(C)C)c6ccc7c(c6NC5=O)OC=CC(O7)(C)C)N(C3=O)C)O
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