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Selectively inhibits P-glycoprotein. Effectively reverses Pgp-mediated drug resistance in NCI.ADR cells, but has not effect on the drug sensitivities of MCF7/VP cells that overexpress MRP1.

Additional Information

Synonyms	N-(1-Benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenyl-acetamide
Product #	P-1267
Chemical Name	N-(1-Benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenyl-acetamide
Formula	C26H23N3O
MW	393.5
Appearance	White Powder
Purity	98%
Solubility	Soluble in ethanol or DMSO
Storage Temp	-20°C

Additional Information

MDL Number	MFCD03452998
ChemACX	X1343411-4
InChI	InChI=1S/C26H23N3O/c30-24(17-19-9-3-1-4-10-19)28-25-21-13-7-8-14-23(21)27-26-22(25)15-16-29(26)18-20-11-5-2-6-12-20/h1-14H,15-18H2,(H,27,28,30)
SMILES	C1CN(C2=NC3=CC=CC=C3C(=C21)NC(=O)CC4=CC=CC=C4)CC5=CC=CC=C5