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上海拜力生物科技公司
Tel:400-968-7988    021-33779008
EZSolution SB-431542
品牌：AG Scientific
貨號：
規(guī)格：1 mg
貨期：
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CAS:301836-41-9Formula:C22H18N4O3MW:384.39Appearance:LiquidPurity:98%
商品詳情 參考文獻(xiàn) 相關(guān)資料

SB-431542 is a potent and selective inhibitor of TGF-β superfamily type I activin receptor-like kinase (ALK) receptors, specifically ALK4, ALK5 and ALK7. Inhibition of TGF-β signaling is known to induce the de-repression of epithelial fate and thus was hypothesized to benefit the reprogramming process.?

Additional Information

Synonyms4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
Product #E-2320
CAS #301836-41-9
Chemical Name4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
FormulaC22H18N4O3
MW384.39
AppearanceLiquid
Purity98%
Melting Point315.72 °C
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseA specific and selective inhibitor of TGF-? type I ALK receptors and Smad3.It also suppressed the TGF-beta-induced proliferation of osteosarcoma

Additional Information

MDL NumberMFCD05865244
ChemACXX1430393-8
InChIInChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
SMILESc1ccnc(c1)c2c(nc([nH]2)c3ccc(cc3)C(=O)N)c4ccc5c(c4)OCO5
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