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上海拜力生物科技公司
Tel:400-968-7988    021-33779008
Herbimycin A, Streptomyces Hygroscopicus
品牌：AG Scientific
貨號：
規(guī)格：100 ug
貨期：
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CAS:70563-58-5Formula:C30H42N2O9MW:574.7Appearance:YellowPowderPurity:98%
商品詳情 參考文獻 相關(guān)資料

A benzoquinoid ansamycin antibiotic that acts as a cell permeable inhibitor of tyrosine kinase and inducer of Heat Shock Proteins. Hsp90 inhibitor. Demonstrates anti-angiogenesis activity.

Additional Information

SynonymsAntibiotic TAN 420F
Product #H-1050
CAS #70563-58-5
Chemical Name[(2R,3S,5S,6R,7S,8E,10S,11S,12Z,14E)-2,5,6,11-TETRAMETHOXY-3,7,9,15-TETRAMETHYL-16,20,22-TRIOXO-17-AZABICYCLO[16.3.1]DOCOSA-1(21),8,12,14,18-PENTAEN-10-YL] CARBAMATE
FormulaC30H42N2O9
MW574.7
AppearanceYellow Powder
Purity98%
SolubilitySoluble in Water, Methanol, and DMSO
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseEffect of herbimycin A, an inhibitor of tyrosine kinase, on protein tyrosine kinase activity and phosphotyrosyl proteins of Ph1-positive leukemia cells

Additional Information

MDL NumberMFCD00151702
ChemACXX1091564-1
InChIInChI=1S/C30H42N2O9/c1-16-10-9-11-23(37-5)28(41-30(31)36)18(3)12-17(2)27(40-8)24(38-6)13-19(4)26(39-7)21-14-20(33)15-22(25(21)34)32-29(16)35/h9-12,14-15,17,19,23-24,26-28H,13H2,1-8H3,(H2,31,36)(H,32,35)/b11-9-,16-10+,18-12+/t17-,19-,23-,24-,26+,27+,28-/m0/s1
SMILESC[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=CC=C(C(=O)NC2=CC(=O)C=C([C@@H]1OC)C2=O)/C)OC)OC(=O)N)C)C)OC)OC
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