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Cell-permeable. Selectively inhibits the tyrosine kinase activity of Jak3 with an ICvalue of 78 M without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases. Also helps to induce rat bone marrow stromal cells (MSCs) to neuronal cells.

Additional Information

Synonyms	4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol,WHI-P131
Product #	W-2482
CAS #	202475-60-3
Chemical Name	4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol
Formula	C16H15N3O3
MW	297.31
Appearance	White to off-white Solid
Purity	98% by TLC
Solubility	DMSO (~50mg/ml
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	JAK3 kinase inhibitor use in cancer

Additional Information

MDL Number	MFCD01862614
ChemACX	X1863890-1
InChI	InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)
SMILES	COc1cc2c(cc1OC)ncnc2Nc3ccc(cc3)O