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A useful fluorogenic substrate for neutrophil elastase. Cleavage of this peptide by the enzyme generates a strongly fluorescent AFC that is monitored fluorometrically. ex: 380 nm;em: 500 nm.

Additional Information

Synonyms	MeOSuc -Ala-Ala-Pro-Val AFC; MeOSuc-AAPV-AFC
Product #	E-2302
Chemical Name	MeOSuc - Ala - Ala - Pro - Val – AFC; MeOSuc-AAPV-AFC
Formula	C31H38N5O9F3
MW	681.67
Appearance	Lyophilized Solid
Purity	99% by HPLC
Solubility	Soluble in DMSO
Storage Temp	-20°C
Use	A fluorogenic substrate used to assay elastase activity

Additional Information

MDL Number	MFCD00155600
InChI	InChI=1S/C31H38F3N5O9/c1-15(2)26(29(45)37-18-8-9-19-20(31(32,33)34)14-25(42)48-22(19)13-18)38-28(44)21-7-6-12-39(21)30(46)17(4)36-27(43)16(3)35-23(40)10-11-24(41)47-5/h8-9,13-17,21,26H,6-7,10-12H2,1-5H3,(H,35,40)(H,36,43)(H,37,45)(H,38,44)/t16-,17-,21-,26-/m0/s1
SMILES	C[C@@H](C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)Nc2ccc3c(cc(=O)oc3c2)C(F)(F)F)NC(=O)CCC(=O)OC
Peptide Sequence	MEOSUC-ALA-ALA-PRO-VAL-AFC