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上海拜力生物科技公司
Tel:400-968-7988    021-33779008
Curcumin, Curcuma longa (High Purity)
品牌：AG Scientific
貨號(hào)：
規(guī)格：10 mg
貨期：
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CAS:458-37-7Formula:C21H20O6MW:368.38Appearance:Orange-yellowSolidPurity:98%
商品詳情 參考文獻(xiàn) 相關(guān)資料

Cell-permeable. An antioxidant and dual inhibitor of 5-lipoxygenase (IC= 8 M)and cyclooxygenase (COX) (IC= 52 M). Also inhibits glutathione S-transferase,induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Also shown to be a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, inhibiting the acetylation of histones H3 and H4 with an ICof ~25 M. Does not affect p300/CREB binding protein-associated factor (PCAF).

Additional Information

Synonyms1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane
Product #C-2275
CAS #458-37-7
Chemical Name1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane
FormulaC21H20O6
MW368.38
AppearanceOrange-yellow Solid
Purity98%
SolubilityDMSO (25 mg/ml) or EtOH (10 mg/ml)
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseCurcumin (Synthetic), a phenolic pigment originally isolated from Curcuma longa (tumeric) has reported antioxident, anticancer and anti-inflammatory actvities

Additional Information

MDL NumberMFCD00008365
ChemACXX1001092-3
InChIInChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
SMILESCOc1c(ccc(c1)/C=C/C(=O)CC(=O)/C=C/c2cc(c(cc2)O)OC)O
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