FGF-10 is a heparin-binding growth factor that belongs to the FGF family.? Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation.? FGF-10 is most related to KGF/FGF-7, and is expressed during the development and, preferentially, in ***** lungs.? It signals through the FGFR 2b.? Recombinant Human FGF-10 is a 19.3 kDa protein consisting of 170 amino acid residues.
Manufactured using all Animal-Free reagents.
Source:
E.coli
Synonyms:
Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2
AA Sequence:
MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS
Purity:
≥ 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors.? The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg.
