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IL-7 is a hematopoietic growth factor that primarily affects early B and T cells.? Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2.? Human and murine IL-7 is cross-species reactive.? Recombinant Murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues.

Source: E.coli

Synonyms: Lymphopoietin 1(LP-1), pre-B cell factor

AA Sequence: MECHIKDKEG KAYESVLMIS IDELDKMTGT DSNCPNNEPN FFRKHVCDDT KEAAFLNRAA RKLKQFLKMN ISEEFNVHLL TVSQGTQTLV NCTSKEEKNV KEQKKNDACF LKRLLREIKT CWNKILKGSI

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is?≤ 0.2 ng/ml, corresponding to a specific activity of?≥ 5 x 10⁶ units/mg.

Note:

1mg will be provided as 2x500μg.