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DiscoverX PI3 Kinase (p110alpha(E545K) p85alpha), murine 14-781
品牌：Eurofins DiscoverX
貨號：14-781
規(guī)格：14-781
貨期：DiscoverX
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品牌：DiscoverX 品名：PI3 Kinase (p110α(E545K)/p85α), murine 貨號：14-781 規(guī)格：10 μg
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品牌：DiscoverX
品名：PI3 Kinase (p110α(E545K)/p85α), murine
貨號：14-781 
規(guī)格：10 μg


簡要說明：

PI3 Kinase (p110α(E545K)/p85α), murine

Complex of N-terminal 6His-tagged recombinant, murine full length p110α containing the mutation E545K and untagged, recombinant, full length murine p85α. The E545K substitution is associated with a number of human cancers. This residue is conserved between the human and murine sequences of p110α. Combined in vitro and in vivo studies have shown that this mutation confers higher lipid kinase activity than wild type, and is able to induce oncogenic transformation.


產(chǎn)品介紹：

Target
PI3Kα/p85α
Expression System
Expressed by baculovirus in Sf21 insect cells
Application
Kinase Assay
Molecular Weight
129 kDa (p110α Ε545Κ), 83.6 kDa (p85α)
Accession Number
NM_006218.2
Species
Mouse
Tag
6His
Purification Method
Ni2+/NTA-agarose
Storage
6 months at -70°C
Bulk Sizes
Inquire



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