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DiscoverX PI3 Kinase (p110alpha(E545K) p85alpha) 14-783-K
品牌：Eurofins DiscoverX
貨號：14-783-K
規(guī)格：14-783-K
貨期：DiscoverX
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品牌：DiscoverX 品名：PI3 Kinase (p110α(E545K)/p85α) 貨號：14-783-K 規(guī)格：Bulk

商品詳情 參考文獻(xiàn) 相關(guān)資料

品牌：DiscoverX
品名：PI3 Kinase (p110α(E545K)/p85α)
貨號：14-783-K  
規(guī)格：Bulk 


簡要說明：

PI3 Kinase (p110α(E545K)/p85α)

Complex of N-terminal 6His-tagged recombinant, human full length p110α containing the mutation E545K and untagged, recombinant, full length human p85α. The E545K substitution is a somatic mutation in p110α that has been associated with tumours of the colon and brain. Combined in vitro and in vivo studies have shown that this mutation confers higher lipid kinase activity than wild type, and is able to induce oncogenic transformation.


產(chǎn)品介紹：

Target
PI3Kα/p85α
Expression System
Expressed by baculovirus in Sf21 insect cells
Application
Kinase Assay
Molecular Weight
125.3 kDa (p110α E542K), 83.7 kDa (p85α)
Accession Number
NM_006218.2
Species
Human
Tag
6His
Purification Method
Ni2+/NTA-agarose
Storage
6 months at -70°C
Bulk Sizes
Inquire



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