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DiscoverX TrkC, active 14-922
品牌：Eurofins DiscoverX
貨號：14-922
規(guī)格：14-922
貨期：DiscoverX
應(yīng)用： 點(diǎn)擊這里給我發(fā)消息  咨詢客服

品牌：DiscoverX 品名：TrkC, active 貨號：14-922 規(guī)格：10 μg
商品詳情 參考文獻(xiàn) 相關(guān)資料

品牌：DiscoverX
品名：TrkC, active
貨號：14-922     
規(guī)格：10 μg

簡要說明：

TrkC, active

N-terminal GST-tagged and C-terminal 6His-tagged recombinant, human TrkC amino acids 510-end. TrkC is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.


產(chǎn)品介紹：

Target
TrkC
Expression System
Expressed by baculovirus in Sf21 insect cells
Application
Kinase Assay
Molecular Weight
64 kDa
Accession Number
NM_002530
Species
Human
Tag
GST, 6His
Purification Method
Glutathione agarose affinity chromatography; Gel filtration
Content
Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Storage
6 months at -70°C
Bulk Sizes
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