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品牌：DiscoverX
品名：IKKε, active
貨號(hào)：14-926-K       
規(guī)格：Bulk 

簡(jiǎn)要說(shuō)明：

N-terminal FLAG, GST-tagged recombinant, human IKKε full length. IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death.

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